![]() ![]() However, the limited data on alternative antiemetic therapies and capsaicin's favorable risk-benefit profile make it a reasonable adjunctive treatment option.ĭrug abuse evidence-based medicine gastroenterology nausea/vomiting pharmaceutical care. Make sure to drink as much water as possible since dehydration can cause a lot of intestinal pain. A diagnosis of cannabis hyperemesis syndrome was made based on history of chronic marijuana use and otherwise negative workup. Data Sources: A literature search using keywords related to cannabinoids, emesis, and capsaicin was performed in. The objective of this study is to systematically review the efficacy data for capsaicin in CHS. Conclusion: Current data for capsaicin efficacy in CHS is of low methodological quality. Heat pads and really hot baths or showers will provide you a lot more relief than the capsaicin cream. Intravenous fluids, antiemetics, and morphine were started for pain control with no symptomatic improvement. Capsaicin is recommended as a reasonable first-line treatment approach for CHS despite limited clinical evidence regarding its use. Your GP can prescribe capsaicin as a low-dose cream for nerve pain. Relevance to Patient Care and Clinical Practice: Capsaicin use was described as beneficial in all case series and case reports however, both retrospective cohort studies were unable to find a significant benefit for capsaicin on primary outcomes (emergency department length of stay). Common side effects include a dry mouth, constipation, dizziness and drowsiness. ![]() ![]() Published abstracts were in the form of case reports (n = 1), case series (n = 3), and retrospective cohort studies (n = 2). Full-text case reports (n = 3) and case series (n = 2) found capsaicin to be effective in a total of 18 patients. Data Synthesis: A total of 241 articles were screened, of which 5 full-text articles and 6 conference abstracts were included. Study Selection and Data Extraction: Studies and published abstracts in which capsaicin was used for CHS and clinical outcomes were reported were eligible for inclusion. Data Sources: A literature search using keywords related to cannabinoids, emesis, and capsaicin was performed in MEDLINE, CINAHL, and EMBASE from inception through March 31, 2019. dopamine antagonist, topical capsaicin cream to the abdomen and avoidance of. The objective of this study is to systematically review the efficacy data for capsaicin in CHS. CHS is characterised by cyclic episodes of nausea and vomiting in patients. Capsaicin is recommended as a reasonable first-line treatment approach for CHS despite limited clinical evidence regarding its use. Results: All 13 patients experienced symptom relief after administration of capsaicin cream. Objective: Cannabinoid hyperemesis syndrome (CHS) is characterized by cyclic vomiting, abdominal pain, and alleviation of symptoms via hot showers in chronic cannabinoid users. Methods: A query of the electronic health record at both centers identified thirteen patients with documented daily cannabis use and symptoms consistent with CHS who were administered topical capsaicin cream for symptom management. ![]()
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